.spectrum-annotation-fragmentation-map[data-v-ed5c3ac2]{display:grid;justify-items:center;gap:4px;max-width:100%;padding:4px 8px 6px;background:var(--sf-figure-background, #ffffff)}.spectrum-annotation-fragmentation-map__title[data-v-ed5c3ac2]{color:var(--sf-line-primary, #111111);font-family:Arial,Helvetica,sans-serif;font-size:12px;font-weight:800;letter-spacing:0;line-height:1}.spectrum-annotation-fragmentation-map__svg[data-v-ed5c3ac2]{display:block;width:210px;max-width:100%;height:auto;overflow:visible}.fragment-map__atom[data-v-ed5c3ac2]{fill:var(--sf-line-primary, #111111);font-family:IBM Plex Mono,ui-monospace,SFMono-Regular,Menlo,Monaco,Consolas,monospace;font-size:12px;font-weight:400;letter-spacing:0;text-anchor:middle}.fragment-map__subscript[data-v-ed5c3ac2]{fill:var(--sf-line-primary, #111111);font-family:IBM Plex Mono,ui-monospace,SFMono-Regular,Menlo,Monaco,Consolas,monospace;font-size:8px;font-weight:400;text-anchor:middle}.fragment-map__bond[data-v-ed5c3ac2]{stroke:var(--sf-line-primary, #111111);stroke-linecap:round;stroke-width:1.4}.fragment-map__bond--dashed[data-v-ed5c3ac2]{stroke-linecap:butt;stroke-dasharray:3 1.5}.fragment-map__cleavage[data-v-ed5c3ac2]{fill:none;stroke-linecap:round;stroke-linejoin:round;stroke-width:1.6}.ps-shell[data-theme=dark],.sf-figures[data-theme=dark]{color:var(--sf-line-primary, #e5e7eb);fill:var(--sf-line-primary, #e5e7eb)}.ps-shell[data-theme=dark],.sf-figures[data-theme=dark]{stroke:var(--sf-line-primary, #e5e7eb)}@media(prefers-color-scheme:dark){.ps-shell[data-theme=system],.sf-figures[data-theme=system]{background:var(--sf-figure-background, #111821)}.ps-shell[data-theme=system],.sf-figures[data-theme=system]{color:var(--sf-line-primary, #e5e7eb);fill:var(--sf-line-primary, #e5e7eb)}.ps-shell[data-theme=system],.sf-figures[data-theme=system]{stroke:var(--sf-line-primary, #e5e7eb)}}.spectrum-annotation-top[data-v-85be08f1]{display:grid;justify-items:center;gap:4px;width:100%;min-width:0;overflow:visible}.spectrum-annotation-series[data-v-85be08f1]{display:flex;flex-wrap:wrap;justify-content:center;gap:6px 14px;width:100%;padding:2px 10px 0;color:var(--sf-text-muted, #64748b);font-family:var(--sf-font-sans);font-size:10px;line-height:1.3}.spectrum-annotation-series__item[data-v-85be08f1]{display:inline-flex;align-items:center;gap:5px;min-width:0}.spectrum-annotation-series__item i[data-v-85be08f1]{width:8px;height:8px;flex:0 0 auto;border-radius:50%}.spectrum-annotation-spans[data-v-85be08f1]{position:relative;width:min(100%,980px);min-width:0;margin:0 auto -2px}.spectrum-annotation-spans__span[data-v-85be08f1]{position:absolute;display:block;min-width:12px;height:11px;border-top:1.5px solid var(--span-color);color:var(--span-color);pointer-events:auto}.spectrum-annotation-spans__span[data-v-85be08f1]:before,.spectrum-annotation-spans__span[data-v-85be08f1]:after{position:absolute;top:-1px;width:0;height:6px;border-left:1.5px solid var(--span-color);content:""}.spectrum-annotation-spans__span[data-v-85be08f1]:before{left:0}.spectrum-annotation-spans__span[data-v-85be08f1]:after{right:0}.spectrum-annotation-spans__label[data-v-85be08f1]{position:absolute;left:50%;top:-11px;max-width:110px;overflow:hidden;font-family:var(--sf-font-sans);font-size:7px;font-weight:800;line-height:1;text-align:center;text-overflow:ellipsis;white-space:nowrap;transform:translate(-50%)}.spectrum-annotation-sequence[data-v-85be08f1]{display:flex;flex-wrap:wrap;justify-content:center;align-content:flex-start;column-gap:2px;row-gap:36px;width:100%;max-width:100%;min-width:0;overflow:visible;padding:30px 12px 26px;background:var(--sf-figure-background, #ffffff)}.spectrum-annotation-sequence__coverage[data-v-85be08f1]{margin:-8px 0 6px;color:var(--sf-text-muted, #64748b);font-family:var(--sf-font-sans);font-size:9px;font-weight:650;line-height:1.2}.spectrum-annotation-sequence__residue[data-v-85be08f1]{flex:0 0 auto;position:relative;display:inline-grid;place-items:center;min-width:22px;min-height:24px;color:var(--sf-line-primary, #111111);font-family:IBM Plex Mono,ui-monospace,SFMono-Regular,Menlo,Monaco,Consolas,monospace;font-size:14px;line-height:1}.spectrum-annotation-sequence__residue--modified .spectrum-annotation-sequence__aa[data-v-85be08f1]{font-weight:800}.spectrum-annotation-sequence__aa[data-v-85be08f1]{position:relative;z-index:2;white-space:nowrap}.spectrum-annotation-sequence__mod[data-v-85be08f1]{position:absolute;top:-20px;left:50%;z-index:3;max-width:min(360px,calc(100vw - 32px));width:max-content;padding:2px 5px;border-radius:2px;background:var(--sf-accent, #7c3aed);color:var(--sf-text-on-accent, #ffffff);font-family:var(--sf-font-sans);font-size:9px;font-weight:800;white-space:nowrap;transform:translate(-50%)}.spectrum-annotation-sequence__lane[data-v-85be08f1]{position:absolute;z-index:4;overflow:visible;pointer-events:none;transform:translate(-50%)}.spectrum-annotation-sequence__lane--bond-left[data-v-85be08f1]{left:-1px}.spectrum-annotation-sequence__lane--bond-right[data-v-85be08f1]{left:calc(100% + 1px)}.spectrum-annotation-sequence__lane--bond-center[data-v-85be08f1]{left:50%}.spectrum-annotation-sequence__lane--top[data-v-85be08f1]{bottom:50%}.spectrum-annotation-sequence__lane--bottom[data-v-85be08f1]{top:50%}.spectrum-annotation-sequence__staple[data-v-85be08f1]{fill:none;stroke-linecap:round;stroke-linejoin:round;stroke-width:1.4}.spectrum-annotation-sequence__staple-label[data-v-85be08f1]{font-family:var(--sf-font-sans);font-size:8px;font-weight:800;paint-order:stroke fill;stroke:var(--sf-figure-background, #ffffff);stroke-linejoin:round;stroke-width:2px;text-anchor:end}.ps-shell[data-theme=dark],.sf-figures[data-theme=dark]{background:var(--sf-figure-background, #111821)}.ps-shell[data-theme=dark],.sf-figures[data-theme=dark]{color:var(--sf-line-primary, #e5e7eb)}.ps-shell[data-theme=dark],.sf-figures[data-theme=dark]{background:var(--sf-accent, #7aa7ff);color:var(--sf-text-on-accent, #ffffff)}@media(prefers-color-scheme:dark){.ps-shell[data-theme=system],.sf-figures[data-theme=system]{background:var(--sf-figure-background, #111821)}.ps-shell[data-theme=system],.sf-figures[data-theme=system]{color:var(--sf-line-primary, #e5e7eb)}.ps-shell[data-theme=system],.sf-figures[data-theme=system]{background:var(--sf-accent, #7aa7ff);color:var(--sf-text-on-accent, #ffffff)}}.stacked-trace-panel[data-v-7e28dfd5]{display:block;min-width:0;background:transparent}.stacked-trace-track[data-v-7e28dfd5]{position:relative;min-width:0;width:100%;cursor:crosshair;touch-action:none;-webkit-user-select:none;user-select:none}.stacked-trace-track__canvas[data-v-7e28dfd5]{display:block;width:100%;height:100%;background:#fff}.stacked-trace-track__empty[data-v-7e28dfd5]{position:absolute;top:0;right:0;bottom:0;left:0;display:grid;place-items:center;color:var(--sf-text-muted, rgba(43, 42, 41, .6));font:12px system-ui,sans-serif;pointer-events:none}:where(.sf-figures){--sf-font-sans: var(--ps-font-sans, "Inter", system-ui, -apple-system, BlinkMacSystemFont, "Segoe UI", sans-serif);--sf-text-primary: var(--ps-text-primary, #2b2a29);--sf-text-muted: var(--ps-text-muted, rgba(43, 42, 41, .6));--sf-text-on-accent: #ffffff;--sf-accent: var(--ps-accent, #2563eb);--sf-border-subtle: var(--ps-divider, rgba(20, 30, 45, .12));--sf-surface-solid: var(--ps-bg-pane, #ffffff);--sf-figure-background: #ffffff;--sf-line-primary: var(--ps-text-primary, #111111);--sf-average-selection: rgba(17, 17, 17, .95);--sf-publication-trace-color: #000000;--sf-radius-sm: var(--ps-radius-sm, 8px);--sf-radius-md: var(--ps-radius-md, 10px);--sf-chrom-ms1-tic: #1f7a1f;--sf-chrom-ms1-bpc: var(--sf-publication-trace-color);--sf-chrom-ms2: #444444;--sf-uv-trace: var(--sf-publication-trace-color);--sf-uv-smoothed-trace: #0891b2;--sf-fit-line: #dc2626;--sf-fit-residual-line: #2563eb;--sf-chart-font-sans: "Arial", sans-serif;--sf-chart-axis: #000000;--sf-chart-background: #ffffff;--sf-chart-bar: #9ADCEE;--sf-chart-bar-negative: #dc2626;--sf-chart-violin-fill: #9ADCEE;--sf-chart-grid: transparent;--sf-chart-range: #000000;--sf-chart-sample-fill: #000000;--sf-chart-sample-stroke: #000000;display:flex;flex-direction:column;gap:12px;min-width:0;color:var(--sf-text-primary);font-family:var(--sf-font-sans)}:where(.ps-shell[data-theme=dark]) :where(.sf-figures),:where(.sf-figures[data-theme=dark]){--sf-text-primary: var(--ps-text-primary, #f6f8fb);--sf-text-muted: var(--ps-text-muted, #8f98aa);--sf-text-on-accent: var(--ps-text-on-accent, #ffffff);--sf-accent: var(--ps-accent, #7aa7ff);--sf-border-subtle: var(--ps-divider, #2a3343);--sf-surface-solid: var(--ps-bg-pane, #111821);--sf-figure-background: var(--ps-bg-pane, #111821);--sf-line-primary: var(--ps-text-primary, #e5e7eb);--sf-average-selection: rgba(246, 248, 251, .95);--sf-publication-trace-color: var(--ps-text-primary, #e5e7eb);--sf-chrom-ms1-tic: #57c76a;--sf-chrom-ms1-bpc: var(--sf-publication-trace-color);--sf-chrom-ms2: #b8c0cc;--sf-uv-trace: var(--sf-publication-trace-color);--sf-uv-smoothed-trace: #67e8f9;--sf-fit-line: #ff5a5f;--sf-fit-residual-line: #7aa7ff;--sf-publication-background: var(--ps-bg-pane, #111821);--sf-publication-axis-color: var(--ps-text-primary, #e5e7eb);--sf-publication-muted-color: var(--ps-text-primary, #e5e7eb);--sf-publication-observed-color: var(--ps-text-primary, #e5e7eb);--sf-publication-fitted-color: #ff5a5f;--sf-publication-residual-color: #7aa7ff;--sf-publication-average-color: var(--ps-accent, #7aa7ff);--sf-publication-title-color: var(--ps-text-primary, #f6f8fb);--sf-publication-nl-color: var(--ps-text-muted, #8f98aa);--sf-publication-range-selected-stroke: rgba(229, 231, 235, .78);--sf-publication-range-stroke: rgba(184, 192, 204, .58);--sf-publication-range-label-color: rgba(184, 192, 204, .74);--sf-chart-font-sans: "Arial", sans-serif;--sf-chart-axis: #000000;--sf-chart-background: #ffffff;--sf-chart-bar: #9ADCEE;--sf-chart-bar-negative: #dc2626;--sf-chart-violin-fill: #9ADCEE;--sf-chart-grid: transparent;--sf-chart-range: #000000;--sf-chart-sample-fill: #000000;--sf-chart-sample-stroke: #000000}.ps-shell[data-theme=dark] .sf-figures.sf-figures,.sf-figures.sf-figures[data-theme=dark]{background:var(--sf-figure-background);color:var(--sf-text-primary)}@media(prefers-color-scheme:dark){:where(.ps-shell[data-theme=system]) :where(.sf-figures),:where(.sf-figures[data-theme=system]){--sf-text-primary: var(--ps-text-primary, #f6f8fb);--sf-text-muted: var(--ps-text-muted, #8f98aa);--sf-text-on-accent: var(--ps-text-on-accent, #ffffff);--sf-accent: var(--ps-accent, #7aa7ff);--sf-border-subtle: var(--ps-divider, #2a3343);--sf-surface-solid: var(--ps-bg-pane, #111821);--sf-figure-background: var(--ps-bg-pane, #111821);--sf-line-primary: var(--ps-text-primary, #e5e7eb);--sf-average-selection: rgba(246, 248, 251, .95);--sf-publication-trace-color: var(--ps-text-primary, #e5e7eb);--sf-chrom-ms1-tic: #57c76a;--sf-chrom-ms1-bpc: var(--sf-publication-trace-color);--sf-chrom-ms2: #b8c0cc;--sf-uv-trace: var(--sf-publication-trace-color);--sf-uv-smoothed-trace: #67e8f9;--sf-fit-line: #ff5a5f;--sf-fit-residual-line: #7aa7ff;--sf-publication-background: var(--ps-bg-pane, #111821);--sf-publication-axis-color: var(--ps-text-primary, #e5e7eb);--sf-publication-muted-color: var(--ps-text-primary, #e5e7eb);--sf-publication-observed-color: var(--ps-text-primary, #e5e7eb);--sf-publication-fitted-color: #ff5a5f;--sf-publication-residual-color: #7aa7ff;--sf-publication-average-color: var(--ps-accent, #7aa7ff);--sf-publication-title-color: var(--ps-text-primary, #f6f8fb);--sf-publication-nl-color: var(--ps-text-muted, #8f98aa);--sf-publication-range-selected-stroke: rgba(229, 231, 235, .78);--sf-publication-range-stroke: rgba(184, 192, 204, .58);--sf-publication-range-label-color: rgba(184, 192, 204, .74);--sf-chart-font-sans: "Arial", sans-serif;--sf-chart-axis: #000000;--sf-chart-background: #ffffff;--sf-chart-bar: #9ADCEE;--sf-chart-bar-negative: #dc2626;--sf-chart-violin-fill: #9ADCEE;--sf-chart-grid: transparent;--sf-chart-range: #000000;--sf-chart-sample-fill: #000000;--sf-chart-sample-stroke: #000000}.ps-shell[data-theme=system] .sf-figures.sf-figures,.sf-figures.sf-figures[data-theme=system]{background:var(--sf-figure-background);color:var(--sf-text-primary)}}:where(.scientific-file-view){width:100%;min-width:0;display:flex;flex-direction:column;gap:var(--ps-space-5, 16px)}:where(.scientific-file-view__workspace){min-width:0;display:flex;flex-direction:column;gap:0}:where(.scientific-file-view__spectrum-navigation){position:relative;z-index:3;height:0;min-height:0;overflow:visible;pointer-events:none}:where(.scientific-file-view__spectrum-back),:where(.scientific-file-view__spectrum-forward){position:absolute;top:4px;left:var(--ps-space-3, 10px);display:inline-flex;align-items:center;gap:4px;min-height:20px;padding:1px 5px;border:0;border-radius:var(--sf-radius-sm);background:transparent;color:var(--sf-accent);font:inherit;font-size:11px;font-weight:var(--ps-weight-semibold, 600);cursor:pointer;pointer-events:auto}:where(.scientific-file-view__spectrum-back:hover){background:color-mix(in srgb,var(--sf-accent) 8%,transparent);color:var(--sf-text-primary)}:where(.scientific-file-view__spectrum-forward){left:auto;right:var(--ps-space-3, 10px)}:where(.scientific-file-view__spectrum-forward:hover){background:color-mix(in srgb,var(--sf-accent) 8%,transparent);color:var(--sf-text-primary)}:where(.scientific-file-view__spectrum-back:focus-visible),:where(.scientific-file-view__spectrum-forward:focus-visible){outline:2px solid var(--sf-accent);outline-offset:1px}:where(.scientific-file-view__spectrum-back kbd),:where(.scientific-file-view__spectrum-forward kbd){display:none}:where(.scientific-file-view__error){margin:0;color:var(--ps-tone-danger, #b42318);font-size:var(--ps-text-sm, 13px);font-weight:var(--ps-weight-semibold, 600)}:where(.ms1-precursor-table){min-width:0;margin-top:var(--ps-space-4, 12px);color:var(--sf-text-primary)}:where(.ms1-precursor-table__header){display:flex;align-items:baseline;justify-content:space-between;gap:var(--ps-space-4, 12px);margin:0 0 var(--ps-space-2, 6px)}:where(.ms1-precursor-table__title){margin:0;color:var(--sf-text-primary);font-size:var(--ps-text-sm, 13px);font-weight:var(--ps-weight-semibold, 600);line-height:1.3}:where(.ms1-precursor-table__master-scan){color:var(--ps-tone-accent, #7c3aed);font-variant-numeric:tabular-nums;text-decoration:underline;text-decoration-thickness:1px;text-underline-offset:2px}:where(.ms1-precursor-table__summary){margin:0;color:var(--sf-text-muted);font-size:var(--ps-text-xs, 11px);line-height:1.35;text-align:right}:where(.ms1-precursor-table__scroll){min-width:0;max-height:min(38vh,420px);overflow:auto;overscroll-behavior-inline:contain;overscroll-behavior-block:contain}:where(.ms1-precursor-table table){width:100%;min-width:1040px;border-collapse:collapse;table-layout:auto;font-size:var(--ps-text-xs, 11px);line-height:1.35}:where(.ms1-precursor-table th,.ms1-precursor-table td){padding:7px 10px;border-top:1px solid var(--sf-line-subtle);text-align:left;vertical-align:middle;white-space:nowrap}:where(.ms1-precursor-table th){position:sticky;z-index:1;top:0;background:var(--sf-surface-solid);color:var(--sf-text-muted);font-weight:var(--ps-weight-semibold, 600)}:where(.ms1-precursor-table tbody tr:last-child td){border-bottom:1px solid var(--sf-line-subtle)}:where(.ms1-precursor-table tbody tr[data-shared-neutral-mass=true]){background:color-mix(in srgb,var(--ps-tone-accent, #7c3aed) 7%,transparent)}:where(.ms1-precursor-table__mass-family){color:var(--ps-tone-accent, #7c3aed);font-weight:var(--ps-weight-semibold, 600)}:where(.ms1-precursor-table__unique){color:var(--sf-text-muted)}:where(.ms1-precursor-table__numeric){font-variant-numeric:tabular-nums}:where(.ms1-precursor-table__scans){display:flex;flex-wrap:wrap;gap:4px}:where(.ms1-precursor-table__scan){display:inline-flex;align-items:baseline;min-height:24px;padding:3px 7px;border:1px solid var(--sf-line-subtle);border-radius:var(--ps-radius-sm, 6px);background:transparent;color:var(--sf-text-primary);font:inherit;font-variant-numeric:tabular-nums;line-height:1.35;text-decoration:none;cursor:pointer}:where(.ms1-precursor-table__scan-number){color:var(--ps-tone-accent, #7c3aed);text-decoration:underline;text-decoration-thickness:1px;text-underline-offset:2px}:where(.ms1-precursor-table__scan:hover){border-color:var(--sf-text-muted);background:color-mix(in srgb,var(--sf-text-primary) 4%,transparent)}:where(.ms1-precursor-table__scan[data-selected=true]){border-color:var(--ps-tone-accent, #7c3aed);background:color-mix(in srgb,var(--ps-tone-accent, #7c3aed) 10%,transparent);color:var(--ps-tone-accent, #7c3aed);font-weight:var(--ps-weight-semibold, 600)}@media(max-width:900px){:where(.ms1-precursor-table__header){align-items:flex-start;flex-direction:column}:where(.ms1-precursor-table__summary){text-align:left}}:where(.spectrum-panel__header,.chrom-panel__header,.uv-panel__header,.fit-panel__header,.chart-panel__header){display:flex;align-items:flex-end;justify-content:space-between;gap:16px;min-width:0}:where(.spectrum-panel__title,.chrom-panel__title,.uv-panel__title,.fit-panel__title,.chart-panel__title){min-width:0;overflow:hidden;text-overflow:ellipsis;white-space:nowrap;margin:0;color:var(--sf-text-primary);font-size:18px;font-weight:600;line-height:1.25;letter-spacing:0}:where(.spectrum-panel__meta,.spectrum-panel__hover-meta,.chrom-panel__meta,.uv-panel__meta,.fit-panel__meta,.chart-panel__meta){box-sizing:border-box;min-width:0;max-width:100%;overflow:hidden;text-overflow:ellipsis;margin-left:auto;color:var(--sf-text-muted);font-size:11px;line-height:1.2;text-align:right;white-space:nowrap}:where(.spectrum-panel__hover-meta){position:absolute;z-index:3;display:flex;min-height:0;align-items:flex-end;justify-content:flex-end;margin-left:0;padding-right:0;pointer-events:none}:where(.spectrum-panel){position:relative}:where(.spectrum-panel__annotation-lane){box-sizing:border-box;min-width:0}:where(.spectrum-panel__annotation-lane[data-fixed-height=true]){height:var(--sf-spectrum-annotation-lane-height);min-height:var(--sf-spectrum-annotation-lane-height);max-height:var(--sf-spectrum-annotation-lane-height);overflow:auto;overscroll-behavior:contain;background:var(--sf-surface-solid)}:where(.spectrum-panel__fragment-info){position:absolute;top:8px;right:8px;z-index:5;display:grid;width:24px;height:24px;place-items:center;border:1px solid rgba(17,24,39,.18);border-radius:999px;background:#ffffffe0;color:#2b2a29;cursor:pointer;font-family:ui-serif,Georgia,serif;font-size:15px;font-style:italic;font-weight:700;line-height:1;box-shadow:0 1px 2px #0f172a14}:where(.spectrum-panel__fragment-info:hover),:where(.spectrum-panel__fragment-info[aria-expanded=true]){border-color:#7c3aed73;background:#fff;color:#7c3aed}:where(.spectrum-panel__fragment-info:focus-visible){outline:2px solid rgba(124,58,237,.35);outline-offset:2px}:where(.spectrum-panel__fragment-popover){position:absolute;top:38px;right:8px;z-index:6;box-sizing:border-box;width:fit-content;max-width:calc(100% - 16px);overflow:visible;border:1px solid rgba(17,24,39,.14);border-radius:8px;background:#fff;box-shadow:0 18px 44px #0f172a2e}:where(.ps-shell[data-theme=dark]) :where(.spectrum-panel__fragment-info),:where(.sf-figures[data-theme=dark]) :where(.spectrum-panel__fragment-info){border-color:var(--sf-border-subtle);background:color-mix(in srgb,var(--sf-figure-background) 88%,transparent);color:var(--sf-text-primary)}:where(.ps-shell[data-theme=dark]) :where(.spectrum-panel__fragment-info:hover),:where(.ps-shell[data-theme=dark]) :where(.spectrum-panel__fragment-info[aria-expanded=true]),:where(.sf-figures[data-theme=dark]) :where(.spectrum-panel__fragment-info:hover),:where(.sf-figures[data-theme=dark]) :where(.spectrum-panel__fragment-info[aria-expanded=true]){border-color:color-mix(in srgb,var(--sf-accent) 45%,var(--sf-border-subtle));background:var(--sf-figure-background);color:var(--sf-accent)}:where(.ps-shell[data-theme=dark]) :where(.spectrum-panel__fragment-popover),:where(.sf-figures[data-theme=dark]) :where(.spectrum-panel__fragment-popover){border-color:var(--sf-border-subtle);background:var(--sf-figure-background);color:var(--sf-text-primary)}@media(prefers-color-scheme:dark){:where(.ps-shell[data-theme=system]) :where(.spectrum-panel__fragment-info),:where(.sf-figures[data-theme=system]) :where(.spectrum-panel__fragment-info){border-color:var(--sf-border-subtle);background:color-mix(in srgb,var(--sf-figure-background) 88%,transparent);color:var(--sf-text-primary)}:where(.ps-shell[data-theme=system]) :where(.spectrum-panel__fragment-info:hover),:where(.ps-shell[data-theme=system]) :where(.spectrum-panel__fragment-info[aria-expanded=true]),:where(.sf-figures[data-theme=system]) :where(.spectrum-panel__fragment-info:hover),:where(.sf-figures[data-theme=system]) :where(.spectrum-panel__fragment-info[aria-expanded=true]){border-color:color-mix(in srgb,var(--sf-accent) 45%,var(--sf-border-subtle));background:var(--sf-figure-background);color:var(--sf-accent)}:where(.ps-shell[data-theme=system]) :where(.spectrum-panel__fragment-popover),:where(.sf-figures[data-theme=system]) :where(.spectrum-panel__fragment-popover){border-color:var(--sf-border-subtle);background:var(--sf-figure-background);color:var(--sf-text-primary)}}:where(.chrom-panel__meta){padding-right:var(--sf-chrom-track-label-right-inset, 12px);position:relative;overflow:visible}:where(.uv-panel__header){display:block}:where(.uv-panel__title){width:100%}:where(.uv-panel__footer){min-width:0;color:var(--sf-text-muted);font-size:11px;line-height:1.2}:where(.ps-shell[data-theme=dark]) :where(.uv-panel__header,.uv-panel__footer),:where(.sf-figures[data-theme=dark].uv-panel) :where(.uv-panel__header,.uv-panel__footer){background:var(--sf-figure-background);-webkit-user-select:none;user-select:none}:where(.ps-shell[data-theme=dark]) :where(.uv-panel__title,.uv-panel__info)::selection,:where(.sf-figures[data-theme=dark].uv-panel) :where(.uv-panel__title,.uv-panel__info)::selection{background:var(--sf-figure-background);color:inherit}@media(prefers-color-scheme:dark){:where(.ps-shell[data-theme=system]) :where(.uv-panel__header,.uv-panel__footer),:where(.sf-figures[data-theme=system].uv-panel) :where(.uv-panel__header,.uv-panel__footer){background:var(--sf-figure-background);-webkit-user-select:none;user-select:none}:where(.ps-shell[data-theme=system]) :where(.uv-panel__title,.uv-panel__info)::selection,:where(.sf-figures[data-theme=system].uv-panel) :where(.uv-panel__title,.uv-panel__info)::selection{background:var(--sf-figure-background);color:inherit}}:where(.spectrum-panel__info,.chrom-panel__info){font-variant-numeric:tabular-nums;transition:opacity .15s ease}:where(.chrom-panel__info){display:inline-block;max-width:100%}:where(.chrom-panel__info-text){min-width:0;overflow:visible;white-space:nowrap}:where(.uv-panel__info){display:inline-block;max-width:100%;text-align:left;font-variant-numeric:tabular-nums;white-space:normal;transition:opacity .15s ease}:where(.spectrum-panel__info--hidden,.chrom-panel__info--hidden){opacity:0}:where(.uv-panel__info--hidden){opacity:0}:where(.chrom-panel__precursor){margin-left:6px;color:var(--sf-text-primary);font-weight:600}:where(.chrom-panel__precursor-link){-webkit-appearance:none;-moz-appearance:none;appearance:none;display:inline;margin:0;padding:0;border:0;background:transparent;color:#7c3aed;cursor:pointer;font:inherit;line-height:inherit;text-decoration:underline;text-decoration-thickness:1px;text-underline-offset:2px;vertical-align:baseline}:where(.chrom-panel__precursor-link:hover,.chrom-panel__precursor-link:focus-visible){color:#6d28d9;outline:none}:where(.chrom-panel__paired-ms2){position:relative;display:inline-flex;align-items:center;gap:2px;color:var(--sf-text-muted);font-weight:500;line-height:inherit;vertical-align:baseline;white-space:nowrap}:where(.chrom-panel__paired-ms2-trigger){-webkit-appearance:none;-moz-appearance:none;appearance:none;box-sizing:border-box;display:inline-grid;width:12px;height:12px;flex:0 0 12px;place-items:center;margin:0;padding:0;border:1px solid transparent;border-radius:3px;background:transparent;color:var(--sf-text-muted);cursor:default;line-height:1}:where(.chrom-panel__paired-ms2-trigger:hover,.chrom-panel__paired-ms2-trigger[aria-expanded=true]){border-color:var(--sf-border-subtle);background:color-mix(in srgb,var(--sf-text-primary) 6%,transparent);color:var(--sf-text-primary)}:where(.chrom-panel__paired-ms2-trigger-icon){width:0;height:0;border-top:3px solid currentColor;border-right:3px solid transparent;border-left:3px solid transparent}:where(.chrom-panel__paired-ms2-menu){position:absolute;z-index:20;top:calc(100% + 6px);right:0;box-sizing:border-box;display:flex;width:min(340px,calc(100vw - 32px));max-height:260px;flex-direction:column;overflow:auto;border:1px solid var(--sf-border-subtle);border-radius:8px;background:var(--sf-figure-background);box-shadow:0 14px 34px #0f172a2e;padding:4px;text-align:left}:where(.chrom-panel__paired-ms2-item){display:grid;width:100%;grid-template-columns:minmax(88px,auto) minmax(0,1fr);gap:8px;align-items:baseline;padding:7px 8px;border:0;border-radius:5px;background:transparent;color:var(--sf-text-primary);cursor:default;font:inherit;font-size:11px;text-align:left}:where(.chrom-panel__paired-ms2-item:hover,.chrom-panel__paired-ms2-item:focus-visible){background:color-mix(in srgb,var(--sf-accent) 12%,transparent);outline:none}:where(.chrom-panel__paired-ms2-item-scan){font-weight:600;white-space:nowrap}:where(.chrom-panel__paired-ms2-item-detail){min-width:0;overflow:hidden;color:var(--sf-text-muted);text-overflow:ellipsis;white-space:nowrap}:where(.spectrum-track){position:relative;min-width:0;overflow:hidden;overscroll-behavior:contain;contain:layout paint style;border-radius:8px;background:var(--sf-surface-solid);cursor:crosshair;touch-action:none;-webkit-user-select:none;user-select:none}:where(.spectrum-panel[data-spectrum-profile=publication-ms]){--sf-surface-solid: #ffffff;--sf-line-primary: #010101}:where(.spectrum-track[data-spectrum-profile=publication-ms]){flex:0 0 auto;min-width:0;border-radius:0;background:#fff;box-shadow:none}:where(.ps-shell[data-theme=dark]) :where(.spectrum-panel[data-spectrum-profile=publication-ms]),:where(.sf-figures[data-theme=dark].spectrum-panel[data-spectrum-profile=publication-ms]){--sf-surface-solid: var(--sf-publication-background);--sf-line-primary: var(--sf-publication-axis-color)}:where(.ps-shell[data-theme=dark]) :where(.spectrum-track[data-spectrum-profile=publication-ms]),:where(.sf-figures[data-theme=dark]) :where(.spectrum-track[data-spectrum-profile=publication-ms]){background:var(--sf-publication-background)}@media(prefers-color-scheme:dark){:where(.ps-shell[data-theme=system]) :where(.spectrum-panel[data-spectrum-profile=publication-ms]),:where(.sf-figures[data-theme=system].spectrum-panel[data-spectrum-profile=publication-ms]){--sf-surface-solid: var(--sf-publication-background);--sf-line-primary: var(--sf-publication-axis-color)}:where(.ps-shell[data-theme=system]) :where(.spectrum-track[data-spectrum-profile=publication-ms]),:where(.sf-figures[data-theme=system]) :where(.spectrum-track[data-spectrum-profile=publication-ms]){background:var(--sf-publication-background)}}:where(.spectrum-track__canvas){display:block;width:100%;height:100%}:where(.spectrum-track__precursor-link){position:absolute;z-index:2;margin:0;padding:0;border:0;border-radius:3px;background:transparent;cursor:pointer}:where(.spectrum-track__precursor-link:focus-visible){outline:2px solid #7c3aed;outline-offset:1px}:where(.spectrum-evidence-table){min-width:0;margin-top:var(--ps-space-3, 10px);color:var(--sf-text-primary)}:where(.spectrum-evidence-table__title){margin:0 0 var(--ps-space-2, 6px);color:var(--sf-text-primary);font-size:var(--ps-text-sm, 13px);font-weight:var(--ps-weight-semibold, 600);line-height:1.3}:where(.spectrum-evidence-table__scroll){min-width:0;overflow-x:auto;overscroll-behavior-inline:contain}:where(.spectrum-evidence-table table){width:100%;min-width:760px;border-collapse:collapse;table-layout:fixed;font-size:var(--ps-text-xs, 11px);line-height:1.35}:where(.spectrum-evidence-table th,.spectrum-evidence-table td){padding:7px 10px;border-top:1px solid var(--sf-line-subtle);text-align:left;vertical-align:top;overflow-wrap:anywhere}:where(.spectrum-evidence-table th){color:var(--sf-text-muted);font-weight:var(--ps-weight-semibold, 600)}:where(.spectrum-evidence-table td:first-child){color:var(--sf-text-primary);font-weight:var(--ps-weight-medium, 500)}:where(.spectrum-evidence-table tbody tr:last-child td){border-bottom:1px solid var(--sf-line-subtle)}:where(.spectrum-track__scan-nav){position:absolute;z-index:4;display:flex;max-width:min(260px,calc(100% - 24px));justify-content:flex-end;pointer-events:auto}:where(.spectrum-track__scan-nav-button,.spectrum-track__scan-nav-input){box-sizing:border-box;min-height:14px;max-width:100%;margin:0;padding:0 3px;border:1px solid transparent;border-radius:3px;background:var(--sf-surface-solid);color:var(--sf-publication-axis-color, var(--sf-text-primary));font-family:Arial,sans-serif;font-size:10px;font-variant-numeric:tabular-nums;font-weight:400;letter-spacing:0;line-height:12px;text-align:right}:where(.spectrum-track__scan-nav-button){-webkit-appearance:none;-moz-appearance:none;appearance:none;overflow:hidden;cursor:text;text-overflow:ellipsis;white-space:nowrap}:where(.spectrum-track__scan-nav-button:hover){border-color:var(--sf-border-subtle)}:where(.spectrum-track__scan-nav-button:focus-visible,.spectrum-track__scan-nav-input:focus){border-color:var(--sf-accent);outline:none}:where(.spectrum-track__scan-nav-input){width:9ch;cursor:text}:where(.spectrum-track__scan-nav-input[aria-invalid=true]){border-color:var(--ps-tone-danger, #b42318)}:where(.spectrum-track__selection,.annotated-spectrum-track__selection){position:absolute;z-index:2;pointer-events:none;border:1px solid rgba(59,130,246,.7);background:#3b82f626}:where(.spectrum-track__empty){position:absolute;top:0;right:0;bottom:0;left:0;display:grid;place-items:center;padding:12px;color:var(--sf-text-muted);font-size:12px;text-align:center}:where(.chrom-panel__tracks){position:relative;display:flex;min-width:0;flex-direction:column;gap:12px}:where(.chrom-panel__association-overlay){position:absolute;top:0;right:0;bottom:0;left:0;z-index:2;overflow:visible;pointer-events:none}:where(.chrom-panel__association-beam){fill:color-mix(in srgb,var(--sf-accent) 14%,transparent);stroke:none}:where(.chrom-panel__association-line){fill:none;stroke:color-mix(in srgb,var(--sf-accent) 72%,transparent);stroke-width:1.25;stroke-linecap:round}:where(.chrom-panel__association-origin){fill:color-mix(in srgb,var(--sf-accent) 18%,transparent);stroke:color-mix(in srgb,var(--sf-accent) 78%,transparent);stroke-width:1.25}:where(.chrom-track){position:relative;min-width:0;overflow:hidden;overscroll-behavior:contain;border-radius:0;background:var(--sf-figure-background);cursor:crosshair;touch-action:none;-webkit-user-select:none;user-select:none}:where(.chrom-track:focus,.chrom-track:focus-visible){outline:none;box-shadow:none}:where(.chrom-track__canvas){display:block;width:100%;height:100%}:where(.chrom-track__selection){position:absolute;z-index:2;pointer-events:none}:where(.chrom-track__selection--zoom){border:1px solid rgba(59,130,246,.7);background:#3b82f626}:where(.chrom-track__selection--average,.chrom-track__average-selection){position:absolute;z-index:3;height:2px;background:var(--sf-average-selection, rgba(17, 17, 17, .95))}:where(.chrom-track__selection--average){pointer-events:none}:where(.chrom-track__average-selection){--sf-average-selection: rgba(17, 17, 17, .95);pointer-events:auto}:where(.chrom-track__average-selection--active){--sf-average-selection: var(--sf-accent)}:where(.chrom-track__selection--average):before,:where(.chrom-track__selection--average):after,:where(.chrom-track__average-selection):before,:where(.chrom-track__average-selection):after{position:absolute;top:-5px;width:2px;height:12px;background:var(--sf-average-selection, rgba(17, 17, 17, .95));content:""}:where(.chrom-track__selection--average):before,:where(.chrom-track__average-selection):before{left:0}:where(.chrom-track__selection--average):after,:where(.chrom-track__average-selection):after{right:0}:where(.chrom-track__average-selection-hit){position:absolute;top:-7px;right:0;bottom:-7px;left:0;width:100%;padding:0;border:0;background:transparent;cursor:pointer}:where(.chrom-track__average-selection-actions){position:absolute;left:50%;bottom:8px;display:inline-flex;gap:3px;opacity:0;pointer-events:none;transform:translate(-50%);transition:opacity .12s ease}:where(.chrom-track__average-selection:hover .chrom-track__average-selection-actions),:where(.chrom-track__average-selection:focus-within .chrom-track__average-selection-actions){opacity:1;pointer-events:auto}:where(.chrom-panel__empty){display:grid;min-height:120px;min-width:0;place-items:center;border:1px dashed var(--sf-border-subtle);border-radius:var(--sf-radius-md);color:var(--sf-text-muted);font-size:12px}:where(.uv-track){position:relative;min-width:0;overflow:hidden;overscroll-behavior:contain;border-radius:0;background:var(--sf-figure-background);cursor:crosshair;touch-action:none;-webkit-user-select:none;user-select:none}:where(.uv-track:focus,.uv-track:focus-visible){outline:none;box-shadow:none}:where(.uv-track__canvas){display:block;width:100%;height:100%}:where(.uv-track__selection){position:absolute;z-index:2;pointer-events:none}:where(.uv-track__selection--zoom){border:1px solid rgba(59,130,246,.7);background:#3b82f626}:where(.uv-track__selection--range,.uv-track__range-selection){position:absolute;z-index:3;height:2px;pointer-events:none;background:var(--sf-average-selection, rgba(17, 17, 17, .95))}:where(.uv-track__range-selection){--sf-average-selection: var(--sf-accent)}:where(.uv-track__selection--range):before,:where(.uv-track__selection--range):after,:where(.uv-track__range-selection):before,:where(.uv-track__range-selection):after{position:absolute;top:-5px;width:2px;height:12px;background:var(--sf-average-selection, rgba(17, 17, 17, .95));content:""}:where(.uv-track__selection--range):before,:where(.uv-track__range-selection):before{left:0}:where(.uv-track__selection--range):after,:where(.uv-track__range-selection):after{right:0}:where(.uv-track__overlay){position:absolute;top:0;right:0;bottom:0;left:0;z-index:4;pointer-events:none}:where(.uv-track__empty){position:absolute;top:0;right:0;bottom:0;left:0;display:grid;place-items:center;padding:12px;color:var(--sf-text-muted);font-size:12px;text-align:center}:where(.fit-track){position:relative;min-width:0;overflow:hidden;overscroll-behavior:contain;border-radius:0;background:var(--sf-surface-solid);cursor:crosshair;touch-action:none;-webkit-user-select:none;user-select:none}:where(.fit-panel[data-fit-profile=publication-ms]){--sf-surface-solid: #ffffff;--sf-line-primary: #010101;--sf-fit-line: #ed2224}:where(.fit-track[data-fit-profile=publication-ms]){background:#fff}:where(.ps-shell[data-theme=dark]) :where(.fit-panel[data-fit-profile=publication-ms]),:where(.sf-figures[data-theme=dark].fit-panel[data-fit-profile=publication-ms]){--sf-surface-solid: var(--sf-publication-background);--sf-line-primary: var(--sf-publication-axis-color);--sf-fit-line: var(--sf-publication-fitted-color)}:where(.ps-shell[data-theme=dark]) :where(.fit-track[data-fit-profile=publication-ms]),:where(.sf-figures[data-theme=dark]) :where(.fit-track[data-fit-profile=publication-ms]){background:var(--sf-publication-background)}@media(prefers-color-scheme:dark){:where(.ps-shell[data-theme=system]) :where(.fit-panel[data-fit-profile=publication-ms]),:where(.sf-figures[data-theme=system].fit-panel[data-fit-profile=publication-ms]){--sf-surface-solid: var(--sf-publication-background);--sf-line-primary: var(--sf-publication-axis-color);--sf-fit-line: var(--sf-publication-fitted-color)}:where(.ps-shell[data-theme=system]) :where(.fit-track[data-fit-profile=publication-ms]),:where(.sf-figures[data-theme=system]) :where(.fit-track[data-fit-profile=publication-ms]){background:var(--sf-publication-background)}}:where(.fit-track__canvas){display:block;width:100%;height:100%}:where(.fit-track__selection){position:absolute;z-index:2;pointer-events:none;border:1px solid rgba(59,130,246,.7);background:#3b82f626}:where(.fit-track__empty){position:absolute;top:0;right:0;bottom:0;left:0;display:grid;place-items:center;padding:12px;color:var(--sf-text-muted);font-size:12px;text-align:center}:where(.chart-track){position:relative;min-width:0;overflow:hidden;border-radius:0;background:var(--sf-figure-background)}:where(.chart-track__canvas){display:block;width:100%;height:100%}:where(.chart-track__empty){position:absolute;top:0;right:0;bottom:0;left:0;display:grid;place-items:center;padding:12px;color:var(--sf-text-muted);font-size:12px;text-align:center}